Silk Road forums
Discussion => Drug safety => Topic started by: gestaltassault2 on January 06, 2013, 05:10 pm
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I'm looking into trying 5-MeO-MiPT...anybody out there with experience with this substance? What was your dose? What were your impressions of it? What do I need to know about it? What should I expect? Any advice?
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*sigh* Limetless doesn't come on the boars anymore
and i think Riotous Defect did a report on 4-HO-DiPT not 5-MeO-MiPT...
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An excellent description here (even if I say so myself) ;) http://silkroadvb5piz3r.onion/silkroad/item/cab018c433
Very cool substance 3mg -12mg. Body tryptamine - very smooth...
BG
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BlueGiraffe!! I was checking out you listings already and you sir are at the top of my list
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Anybody else?
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okay guise, i can be of use here because i have tried 5-meo-mipt! ;D
and a riotous defect reported on 4-ho-mipt, which is miprocin (i got somma dat too XD)
i would say 5-meo-mipt is a very social, friendly tryptamine. the visual effects for me were barely there. very vague tints of colors over my vision, some patterning but the experience was more about the euphoria/sensations it provided than it was about it being a "trip"
ive heard it described as a tryptamine roll and i can totally see where they were coming from with that.
i put about 10 mgs of moxy in a giggle stick full of medical marijuana and a tenth of dmt, and i must say that was UNCOMFORTABLE. it was the most stoned ive been from psychedelics that i can ever remember. when i came down i felt quite at peace but it was a hell of a ride when it was there for sure!
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*sigh* Limetless doesn't come on the boars anymore
and i think Riotous Defect did a report on 4-HO-DiPT not 5-MeO-MiPT...
Limetless does come on the boards and it is an excellent psych if you don't want "too much" if you know what I mean. Extremely euphoric too which is always a bonus in my book.
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*sigh* Limetless doesn't come on the boars anymore
and i think Riotous Defect did a report on 4-HO-DiPT not 5-MeO-MiPT...
Limetless does come on the boards and it is an excellent psych if you don't want "too much" if you know what I mean. Extremely euphoric too which is always a bonus in my book.
totally agree, its the least demanding psychedelic i think ive ever done.
zero mindfuck
zero confusion
zero paranoia.
i can see why someone would sing the praises of moxy for sure
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*sigh* Limetless doesn't come on the boars anymore
and i think Riotous Defect did a report on 4-HO-DiPT not 5-MeO-MiPT...
Limetless does come on the boards and it is an excellent psych if you don't want "too much" if you know what I mean. Extremely euphoric too which is always a bonus in my book.
totally agree, its the least demanding psychedelic i think ive ever done.
zero mindfuck
zero confusion
zero paranoia.
i can see why someone would sing the praises of moxy for sure
Yeah this is why I like it, it's just easy even in large doses.
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Here is what I wrote about it in another thread:
5-MeO-MiPT aka "Moxy" is a psychedelic tryptamine invented by Shulgin, with typical dosages ranging from 6-12mg. Duration of effects seven hours. It's sometimes called the MDMA of the tryptamines because of the emotional opening, increased tactile sensations and erotic feelings it causes. Despite these similarities with MDMA it feels vastly different (at least for me). It gives you a happy, sometimes giggly headspace that can change to loved-up and erotic, given the situation. The body-high is extremely speedy but at the same time much more clean and nice-feeling than cathinones, amphetamines and phenethylamines. It also doesn't have side-effects like jaw-clenching and the comedown is essentially non-existent but most importantly:
No more erectile dysfunction! You just poached that hot chick using MDMA as a confidence-booster? You'll realize what a no-brainer that was when you're about to plow her vagina to shreds and you can't even get your fuck-stick up. You don't need to worry about that with Moxy. It is amazing for fucking without making you trip like 2C-B does.
If you have any questions, just ask me ;)
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Here is what I wrote about it in another thread:
5-MeO-MiPT aka "Moxy" is a psychedelic tryptamine invented by Shulgin, with typical dosages ranging from 6-12mg. Duration of effects seven hours. It's sometimes called the MDMA of the tryptamines because of the emotional opening, increased tactile sensations and erotic feelings it causes. Despite these similarities with MDMA it feels vastly different (at least for me). It gives you a happy, sometimes giggly headspace that can change to loved-up and erotic, given the situation. The body-high is extremely speedy but at the same time much more clean and nice-feeling than cathinones, amphetamines and phenethylamines. It also doesn't have side-effects like jaw-clenching and the comedown is essentially non-existent but most importantly:
No more erectile dysfunction! You just poached that hot chick using MDMA as a confidence-booster? You'll realize what a no-brainer that was when you're about to plow her vagina to shreds and you can't even get your fuck-stick up. You don't need to worry about that with Moxy. It is amazing for fucking without making you trip like 2C-B does.
If you have any questions, just ask me ;)
can't find it in Pikhal :( sounds interesting!!! I hate ED from coke or MDxx ...me personally i get em, just not that stiff!! lulz. but i last forevvva on it once it get up. Felt the need to share that.
Try TiHKAL ;)
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Here is what I wrote about it in another thread:
5-MeO-MiPT aka "Moxy" is a psychedelic tryptamine invented by Shulgin, with typical dosages ranging from 6-12mg. Duration of effects seven hours. It's sometimes called the MDMA of the tryptamines because of the emotional opening, increased tactile sensations and erotic feelings it causes. Despite these similarities with MDMA it feels vastly different (at least for me). It gives you a happy, sometimes giggly headspace that can change to loved-up and erotic, given the situation. The body-high is extremely speedy but at the same time much more clean and nice-feeling than cathinones, amphetamines and phenethylamines. It also doesn't have side-effects like jaw-clenching and the comedown is essentially non-existent but most importantly:
No more erectile dysfunction! You just poached that hot chick using MDMA as a confidence-booster? You'll realize what a no-brainer that was when you're about to plow her vagina to shreds and you can't even get your fuck-stick up. You don't need to worry about that with Moxy. It is amazing for fucking without making you trip like 2C-B does.
If you have any questions, just ask me ;)
can't find it in Pikhal :( sounds interesting!!! I hate ED from coke or MDxx ...me personally i get em, just not that stiff!! lulz. but i last forevvva on it once it get up. Felt the need to share that.
Try TiHKAL ;)
cant believe i missed that xD. pihkal is phenethylamines i have known and loves
tihkal is tryptamines i have known and loved =P
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Here is what I wrote about it in another thread:
5-MeO-MiPT aka "Moxy" is a psychedelic tryptamine invented by Shulgin, with typical dosages ranging from 6-12mg. Duration of effects seven hours. It's sometimes called the MDMA of the tryptamines because of the emotional opening, increased tactile sensations and erotic feelings it causes. Despite these similarities with MDMA it feels vastly different (at least for me). It gives you a happy, sometimes giggly headspace that can change to loved-up and erotic, given the situation. The body-high is extremely speedy but at the same time much more clean and nice-feeling than cathinones, amphetamines and phenethylamines. It also doesn't have side-effects like jaw-clenching and the comedown is essentially non-existent but most importantly:
No more erectile dysfunction! You just poached that hot chick using MDMA as a confidence-booster? You'll realize what a no-brainer that was when you're about to plow her vagina to shreds and you can't even get your fuck-stick up. You don't need to worry about that with Moxy. It is amazing for fucking without making you trip like 2C-B does.
If you have any questions, just ask me ;)
Great description! Though I wouldn't call the body-high "speedy" necessarily - smoother than that but definitely very full...
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Here is what I wrote about it in another thread:
5-MeO-MiPT aka "Moxy" is a psychedelic tryptamine invented by Shulgin, with typical dosages ranging from 6-12mg. Duration of effects seven hours. It's sometimes called the MDMA of the tryptamines because of the emotional opening, increased tactile sensations and erotic feelings it causes. Despite these similarities with MDMA it feels vastly different (at least for me). It gives you a happy, sometimes giggly headspace that can change to loved-up and erotic, given the situation. The body-high is extremely speedy but at the same time much more clean and nice-feeling than cathinones, amphetamines and phenethylamines. It also doesn't have side-effects like jaw-clenching and the comedown is essentially non-existent but most importantly:
No more erectile dysfunction! You just poached that hot chick using MDMA as a confidence-booster? You'll realize what a no-brainer that was when you're about to plow her vagina to shreds and you can't even get your fuck-stick up. You don't need to worry about that with Moxy. It is amazing for fucking without making you trip like 2C-B does.
If you have any questions, just ask me ;)
Great description! Though I wouldn't call the body-high "speedy" necessarily - smoother than that but definitely very full...
Yeah, the word "full" describes it pretty well :)
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
Yes, because it's a 5-HT2A agonist. I can't say anything about (cross-)tolerance but it will definitely be an issue to some extent if you do Moxy or other 5-HT2A agonists regularly.
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
i bought some along with some 25b-nbome from enboom.
i took them both together when i first got them -_-. shit was overwhelming. but i needed a long break after that for the moxy to work again.
definitely affected by tolerance.
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
i bought some along with some 25b-nbome from enboom.
i took them both together when i first got them -_-. shit was overwhelming. but i needed a long break after that for the moxy to work again.
definitely affected by tolerance.
Okay, I've done some research in the last half hour and it turns out I was... well, not really wrong but I wasn't correct either.
This is the most detailed pharmacological profile of 5-MeO-MiPT I could find:
4.00 5-HT1A
3.79 5-HT7
3.74 5-HT1D
3.32 5-HT2B
2.98 5-HT6
2.85 Alpha-2A
2.61 5-HT1B
2.44 5-HT2A
2.29 Alpha-2C
2.15 Imidazoline1
2.13 Sigma-2
2.11 5-HT5A
1.86 Alpha-2B
1.75 5-HT2C
1.70 D3
1.55 5-HT1E
1.41 H1
1.29 D4
1.28 SERT
Sooo, this is very interesting. Not much is known about the pharmacology of 25b except that it has a crazy affinity to 5-HT2A. It's also standing to reason that it has at least some affinity to 5-HT2C because it's an analog of 2C-B.
You said that you needed a long break for Moxy to work again, which should not happen because 5-HT2A and 5-HT2C are a rather minor part in the pharmacology of Moxy so even if those receptors downregulated themselves because of the 25b, the effects of Moxy shouldn't be affected very much.
So, what does this mean? The only explanation I can come up with is that 25b binds to some of the receptors that Moxy binds to, resulting in downregulation and cross-tolerance.
Of course there is no proof for this hypothesis until 25b is tested for its affinity to other receptors.
If anyone has any suggestions or finds any useful info on this, please post them here :)
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
Pls fill the answer into this list here:
Tolerance of various drugs
http://dkn255hz262ypmii.onion/index.php?topic=102960.0
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
i bought some along with some 25b-nbome from enboom.
i took them both together when i first got them -_-. shit was overwhelming. but i needed a long break after that for the moxy to work again.
definitely affected by tolerance.
Okay, I've done some research in the last half hour and it turns out I was... well, not really wrong but I wasn't correct either.
This is the most detailed pharmacological profile of 5-MeO-MiPT I could find:
4.00 5-HT1A
3.79 5-HT7
3.74 5-HT1D
3.32 5-HT2B
2.98 5-HT6
2.85 Alpha-2A
2.61 5-HT1B
2.44 5-HT2A
2.29 Alpha-2C
2.15 Imidazoline1
2.13 Sigma-2
2.11 5-HT5A
1.86 Alpha-2B
1.75 5-HT2C
1.70 D3
1.55 5-HT1E
1.41 H1
1.29 D4
1.28 SERT
Sooo, this is very interesting. Not much is known about the pharmacology of 25b except that it has a crazy affinity to 5-HT2A. It's also standing to reason that it has at least some affinity to 5-HT2C because it's an analog of 2C-B.
You said that you needed a long break for Moxy to work again, which should not happen because 5-HT2A and 5-HT2C are a rather minor part in the pharmacology of Moxy so even if those receptors downregulated themselves because of the 25b, the effects of Moxy shouldn't be affected very much.
So, what does this mean? The only explanation I can come up with is that 25b binds to some of the receptors that Moxy binds to, resulting in downregulation and cross-tolerance.
Of course there is no proof for this hypothesis until 25b is tested for its affinity to other receptors.
If anyone has any suggestions or finds any useful info on this, please post them here :)
yeah idk, i definitely liked the 25b the most out of my nbome experiences but it lasts for a very long time for me, 10 hours after ingesting i still had waving walls and a spaced out mind.
that experience of 25b was honestly amazing. i saw some very awe-inspiring things, and left my body at some points, while still seeing through my eyes. (was like i could see what my body was seeing, but my vision was more broad than that. like i was in space, looking at a screen that projected what i was seeing.
cool experience but definitely downgraded a few of my attempts at moxy after words.
like i said i would definitely take a break.
although i will say that taking moxy after was still a mood lift, just nothing to what its like without tolerance.
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
i bought some along with some 25b-nbome from enboom.
i took them both together when i first got them -_-. shit was overwhelming. but i needed a long break after that for the moxy to work again.
definitely affected by tolerance.
Okay, I've done some research in the last half hour and it turns out I was... well, not really wrong but I wasn't correct either.
This is the most detailed pharmacological profile of 5-MeO-MiPT I could find:
4.00 5-HT1A
3.79 5-HT7
3.74 5-HT1D
3.32 5-HT2B
2.98 5-HT6
2.85 Alpha-2A
2.61 5-HT1B
2.44 5-HT2A
2.29 Alpha-2C
2.15 Imidazoline1
2.13 Sigma-2
2.11 5-HT5A
1.86 Alpha-2B
1.75 5-HT2C
1.70 D3
1.55 5-HT1E
1.41 H1
1.29 D4
1.28 SERT
Sooo, this is very interesting. Not much is known about the pharmacology of 25b except that it has a crazy affinity to 5-HT2A. It's also standing to reason that it has at least some affinity to 5-HT2C because it's an analog of 2C-B.
You said that you needed a long break for Moxy to work again, which should not happen because 5-HT2A and 5-HT2C are a rather minor part in the pharmacology of Moxy so even if those receptors downregulated themselves because of the 25b, the effects of Moxy shouldn't be affected very much.
So, what does this mean? The only explanation I can come up with is that 25b binds to some of the receptors that Moxy binds to, resulting in downregulation and cross-tolerance.
Of course there is no proof for this hypothesis until 25b is tested for its affinity to other receptors.
If anyone has any suggestions or finds any useful info on this, please post them here :)
Fuck, very interesting information! Thank you... Do you have a link to where I can find that kind of detail on receptor affinity for other drugs as well?
BG
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any information regarding tolerance with this substance? if i do moxy one day and try it again the following day or following week or so will there be any decrease in intensity, effect, or potency? does it have any cross tolerance with other substances?
also i'm guessing that the standard MAOIs potentiate the effects and SSRIs block the effects rule applies as well right?
i bought some along with some 25b-nbome from enboom.
i took them both together when i first got them -_-. shit was overwhelming. but i needed a long break after that for the moxy to work again.
definitely affected by tolerance.
Okay, I've done some research in the last half hour and it turns out I was... well, not really wrong but I wasn't correct either.
This is the most detailed pharmacological profile of 5-MeO-MiPT I could find:
4.00 5-HT1A
3.79 5-HT7
3.74 5-HT1D
3.32 5-HT2B
2.98 5-HT6
2.85 Alpha-2A
2.61 5-HT1B
2.44 5-HT2A
2.29 Alpha-2C
2.15 Imidazoline1
2.13 Sigma-2
2.11 5-HT5A
1.86 Alpha-2B
1.75 5-HT2C
1.70 D3
1.55 5-HT1E
1.41 H1
1.29 D4
1.28 SERT
Sooo, this is very interesting. Not much is known about the pharmacology of 25b except that it has a crazy affinity to 5-HT2A. It's also standing to reason that it has at least some affinity to 5-HT2C because it's an analog of 2C-B.
You said that you needed a long break for Moxy to work again, which should not happen because 5-HT2A and 5-HT2C are a rather minor part in the pharmacology of Moxy so even if those receptors downregulated themselves because of the 25b, the effects of Moxy shouldn't be affected very much.
So, what does this mean? The only explanation I can come up with is that 25b binds to some of the receptors that Moxy binds to, resulting in downregulation and cross-tolerance.
Of course there is no proof for this hypothesis until 25b is tested for its affinity to other receptors.
If anyone has any suggestions or finds any useful info on this, please post them here :)
Fuck, very interesting information! Thank you... Do you have a link to where I can find that kind of detail on receptor affinity for other drugs as well?
BG
It's from "Psychedelics and the Human Receptorome" by Thomas S. Ray.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0009019
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Awesome thanks :)
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How does Moxy compare to 2C-B? Similarities? Differences?
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How does Moxy compare to 2C-B? Similarities? Differences?
moxy is more of a subtle mood lift. doesnt last that long and its very gentle on you.
not really anything like 2c-b other than the fact that they are both labeled as psychedelics.|
2c-b was there wether i wanted it to be or not. moxy on the other hand is something that (in my opinion) you can choose to embrace or deny.
and like i said, moxy isnt "strong" at all in my opinion. very forgiving substance like ballz said.
just get it, try it, and decide for yourself what the differences are!
btw i tried to keep this unbiased, but i personally will pick tryptamines over phenethylamines for the rest of my days.
i will always be down to try something but when it boils down to it, id much rather have the tryptamine experience.
although i prefer more challenging tryptamines like psilocin/psilocybin and dmt, as well as some of the 4 subbed tryptamines
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How does Moxy compare to 2C-B? Similarities? Differences?
Always a challenging type of question... But I'll have a crack at it!
Moxy:
Tryptamine
Active at 3mg - 12mg
Duration 4-6 hours
2C-B:
Phenethylamine
Active at 5mg - 30mg
Duration 4-6 hours
They are both psychedelic entactogens, both increase eroticism, both are functionally good for sex, both are mildly stimulating - so many similarities.
I would say that 2C-B is potentially more visual, and perhaps a richer and deeper psychedelic (in a certain way), but then Moxy has a deep tryptamine opulence that rivals 2C-B.
Moxy is kind of a two-phase drug; initially only empathic, tactile and stimulating, and then becoming more psychedelic as the experience progresses, whereas 2C-B is visually psychedelic from the beginning.
On one level they are profoundly similar, but there are subtle qualities that I'm not even sure I can articulate fully, that make them distinct, i.e. I would clearly know which one I had taken.
Moxy opens the lungs and heart area up more, and also requires more participation with the body to bring out its full character, whereas 2C-B does not require it as much. Both enhance sound/music but I would say that Moxy modifies it more.
I would say 2C-B is better post MDMA than Moxy. Both combine very well with GHB to create excellent tantric psychedelic aphrodisiacs. Moxy is probably more stimulating than 2C-B in the final analysis. I would also say I feel that 2C-B is more grounded in natural bio-chemistry, i.e. it feels as though it exists in the natural "non-human" world somewhere, whereas Moxy does not feel like that to me. Both are good for dancing on.
Both are relatively "gentle"psychedelics, but both can spank you hard if you push the dose; 2C-B at 30mg+ and Moxy at 12mg+
I would say that Moxy is warmer and fuller, and 2C-B is more sparkly and playful - but these are all just subtle, and very general, impressions.
You're gonna have to take 'em both and compare :)
BG
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Very good post, BlueGiraffe, I'd +1 you if I could right now :)
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Mine is berry goooooood
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How does Moxy compare to 2C-B? Similarities? Differences?
Always a challenging type of question... But I'll have a crack at it!
Moxy:
Tryptamine
Active at 3mg - 12mg
Duration 4-6 hours
2C-B:
Phenethylamine
Active at 5mg - 30mg
Duration 4-6 hours
They are both psychedelic entactogens, both increase eroticism, both are functionally good for sex, both are mildly stimulating - so many similarities.
I would saw that 2C-B is potentially more visual, and perhaps a richer and deeper psychedelic (in a certain way), but then Moxy has a deep tryptamine opulence that rivals 2C-B.
Moxy is kind of a two-phase drug; initially only empathic, tactile and stimulating, and then becoming more psychedelic as the experience progresses, whereas 2C-B is visually psychedelic from the beginning.
On one level they are profoundly similar, but there are subtle qualities that I'm not even sure I can articulate, that make them distinct, i.e. I would clearly know which one I had taken.
Moxy opens the lungs and heart area up more, and also requires more participation with the body to bring out its full character, whereas 2C-B does not require it as much. Both enhance sound/music but I would say that Moxy modifies it more.
I would say 2C-B is better post MDMA than Moxy. Both combine very well with GHB to create excellent tantric psychedelic aphrodisiacs. Moxy is probably more stimulating than 2C-B in the final analysis. I would also say I feel that 2C-B is more grounded in natural bio-chemistry, i.e. it feels as though it exists in the natural "non-human" world somewhere, whereas Moxy does not feel like that to me.
Both are relatively "gentle"psychedelics, but both can spank you hard if you push the dose - 2C-B at 30mg+ and Moxy at 12mg+
I would say that Moxy is warmer and fuller, and 2C-B is more sparkly and playful - but these are all just subtle, and very general, impressions.
You're gonna have to take 'em both and compare :)
BG
this is exactly the kind of information i've been looking for!! +1
the reason i ask is because i'll be attending a 3 day festival in a few months and these are a couple of the substances i'm interested in taking with me...
i'm interested particularly in the musical and tactile enhancement without all the mindfuck of classic psychedelics like LSD or psilocybin...
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thanks everyone!!
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How about Moxy-flipping (MDMA + Moxy)?
How should one time the doses for a Moxy-flip?
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How about Moxy-flipping (MDMA + Moxy)?
How should one time the doses for a Moxy-flip?
I have been thinking about this for months now and will definitely try it as soon as I get my hands on some MDMA again.
As for timing, I'd either just drop 'em at the same time or drop the Moxy about 30 minutes before the MDMA.
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Any tried Moxy after MDMA?
As in dropping a 3/6mg of Moxy just as the MDMA peak wears off?
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They say that 5-MeO -MiPT (moxy) became a substitute for 5-MeO-DiPT (foxy) once it became a scheduled substance...what are the similarities and differences between the 2?
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anyone?
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They say that 5-MeO -MiPT (moxy) became a substitute for 5-MeO-DiPT (foxy) once it became a scheduled substance...what are the similarities and differences between the 2?
From what I've read, Moxy is also supposed to have a smoother body load and less side effects.
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Body load is minimal on Moxy depending on your dose of course.
I had around 14-15mg's of Moxy 2 weeks ago and body load was insane, not really heavy, but heavy, it was still very nice though and energy levels were amazing.
Kept me going for nearly 8hrs.
Had zero comedown and felt perfect the next day.
I've had 8mg of Moxy around 12hrs after rolling on Molly and it was very nice and smooth.
If i was to mix MDMA and Moxy together, i would have the Moxy, around 10-12mgs, an hour or 2 in.
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How about Moxy-flipping (MDMA + Moxy)?
How should one time the doses for a Moxy-flip?
I have been thinking about this for months now and will definitely try it as soon as I get my hands on some MDMA again.
As for timing, I'd either just drop 'em at the same time or drop the Moxy about 30 minutes before the MDMA.
I have not tried Moxy but just fwiw, mixing mdma at the same time as other drugs can make for quite the strong come up. I have mixed 200mg M1 with 1.0g mushrooms and the comeup was very strong. I think it's more optimal to time them to synergize differently. That said, if the body load from foxy is minimal I don't think it matters as much. However, I just saw this and thought about my experience and remembered the comeup feeling "crackish" even though I haven't tried crack if that makes sense.
The body load from Moxy is a trippy one so I think it would complement MDMA very well.
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Feel free to mark this as off-topic, but how would you compare Moxy to Mephedrone?
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@ OP:
You need to know that moxy and 25i NBOMe have a cross tolerance if one intends on piggyback dosing by using the next day
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hey guys great thread, never tried this yet but it's gonna happen soon :D
Okay, I've done some research in the last half hour and it turns out I was... well, not really wrong but I wasn't correct either.
This is the most detailed pharmacological profile of 5-MeO-MiPT I could find:
4.00 5-HT1A
3.79 5-HT7
3.74 5-HT1D
3.32 5-HT2B
2.98 5-HT6
2.85 Alpha-2A
2.61 5-HT1B
2.44 5-HT2A
2.29 Alpha-2C
2.15 Imidazoline1
2.13 Sigma-2
2.11 5-HT5A
1.86 Alpha-2B
1.75 5-HT2C
1.70 D3
1.55 5-HT1E
1.41 H1
1.29 D4
1.28 SERT
Sooo, this is very interesting. Not much is known about the pharmacology of 25b except that it has a crazy affinity to 5-HT2A. It's also standing to reason that it has at least some affinity to 5-HT2C because it's an analog of 2C-B.
You said that you needed a long break for Moxy to work again, which should not happen because 5-HT2A and 5-HT2C are a rather minor part in the pharmacology of Moxy so even if those receptors downregulated themselves because of the 25b, the effects of Moxy shouldn't be affected very much.
So, what does this mean? The only explanation I can come up with is that 25b binds to some of the receptors that Moxy binds to, resulting in downregulation and cross-tolerance.
Of course there is no proof for this hypothesis until 25b is tested for its affinity to other receptors.
If anyone has any suggestions or finds any useful info on this, please post them here :)
btw I dont want to come across as a dick, I only want to help clarify some good data, :D and so, I just thought I'd mention that the numbers here that denote receptor "affinity" mean that closer the number is to 4.0 the higher the affinity (attachment to the receptor) of the compound to that receptor
So, on the above chart it shows that moxy has the 'highest affinity' for these guys
4.00 5-HT1A
3.79 5-HT7
3.74 5-HT1D and so on down the chain.......which means that this compound has the 'highest affinity' to the 5-HT1A receptor and so on
the thing about these numbers is that all neurotransmitters, is that they are 'complimentary' and affect each other and SO many 'other' body functions, e.g. via hormone regulation
As much as medical science would LOVE to be able to "categorize" the 'actions' of these neurochemicals...it still has a long way to go, although one can at least get an idea of which compounds affect which 'neural pathways' and so might have 'similar' actions . . . we've still got heaps to learn ???
A bit like how until anandamides (our 'natural' aka endogenous cannabis receptor 'chemicals') were discovered, the effects of cannabis were only being described through known biological processes, which was completely logical, of course, but not completely 'accurate' :P
Currently, they are discovering 'new' neurotransmitters and/or their effects regularly, and the results of some studies have only posed more questions than they've given answers ! :)
Great thread good read, and here's the post from on silk road referred to earlier
A fine creation of the illustrious Dr. Alexander Shulgin, 5-MeO-MIPT (5-methoxy-N-methyl-N-isopropyltryptamine) is one of the very rare Tryptamines that is both a Psychedelic (ala LSD, Mescaline, DMT) and an Entactogen (ala MDMA, 2C-B, MDE).
Chemically, it is a small adjustment (replacing a methyl with an isopropyl group) on the more well-known 5-MeO-DMT, which is found in the venom of the toad Bufo Alvarius and in the resin of the Virola calophylla tree - both used as traditional Shamanic medicines in the Brazilian Amazon.
This replacement of the methyl group with an isopropyl group makes this substance orally active at low doses without needing an MAOI, and also makes the experience less psychedelic and more heart-opening, tactile and pleasurable.
Moxy is an excellent aphrodisiac and sexual enhancer. It is definitely psychedelic at higher doses, but comes on through the body, opening the lungs and creating a deep emotional and tactile fullness. It improves sexual function, increases desire and profoundly enhances mental eroticism, emotional openness and tactile sensitivity.
While it is not the same as empathogens like MDMA, it can be used in a similar way and in similar circumstances. It requires more participation than traditional empathogens and does not “push” you into an opened state. Rather it allows choice on how to feel and act while providing a similar heart-strength. And it creates a more natural, intelligent and coherent euphoria, with a clear mind-space and good energy. Communication is easy.
Moxy works best when it is participated with – through breathing, moving, stretching, dancing and fucking. Any form of light touch or massage will also invigorate and expand Moxy’s activity. Being gently stimulating, it combines well with relaxants such as alcohol (just a little), GHB and 2C-C.
It is also a full Tryptamine with all the associated richness, opulence, class and depth of this family of compounds. Larger doses will definitely provide a deep psychedelic space and will readily open all kinds of doors. But it always maintains the heart and has exquisite balance, so deep states are easily handled and integrated.
Body-load is minimal to non-existent. The experience ends clean without much of a tail, and there is no post-trip downer.
As 5-MeO-MIPT is very potent it, requires very accurate, precise and properly calibrated scales to weigh it safely. This is why we have bulked it up 110:1 with L-Arginine (with a dash of beetroot powder to create a fetching pink colour!) and packed it in Size 1 vegetable cellulose capsules. The L-Arginine is also a vasodilator which works to balance out the mild vasoconstricting effects of nearly all psychedelics - and will allow blood to flow strongly to those organs it needs to flow to ;)
Material identity confirmed by GC-MS and NMR (and of course, bio-assay by me personally). Minimum purity assay of 99.5% by HPLC.
Dosage and Duration:
1-3 capsules, 4-6 hours.
One capsule: Kiss you…
Two capsules: Love you…
Three capsules: Spank you…
Enjoy!
peace love and foxy mungs beans amicos :)
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Feel free to mark this as off-topic, but how would you compare Moxy to Mephedrone?
I had 10 mg of Moxy for the first time (combined with GHB). Compared to Mephedrone it is subtler and still more of a sensual stimulant. Body feels vibrating, like under a weak electrical charge but absolutely pleasant. While being a fan of heavy droning I will shift towards Moxy as the overall experience is less stressful and there is no anxiety at the comedown.
It actually lifted me out of a period of unspecified anxiety and today is the first day where I feel like a tigress again. So definitely a plus for depressed people.
I'd rather compare Moxy to MDMA and say Moxy is the better alternative.
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@ Motek +1 karma to you, excellent post and contribution on how to use powdered bulking agents for dosing at the microgram (ug) level accurately, without having to source various liquids, containers, syringes, and a calculator. Just what the doctor ordered!
As we posted earlier (while high) there are cross tolerance issues, allow us to expand on that earlier post:
We got our Moxy on Thursday, and were in a position to use it immediately (during the day) 300ug that amount came in a baggie smaller than a regular postage stamp!
From the 300ug we combined an eyeball dosage of what may or may not have been 20-30-40ug with a measured 2g GHB around noon Thursday, and had a great sexy time!
Friday evening, we then used used 2400ug (two blotters) 25i NBOMe with THC bumps every whenever the hell we felt like it, and had a euphoric roll.
Last night (Saturday) we eyeballed 20/30ug Moxy but never got any of the earlier sensations (Thursdays roll) , so either the Moxy is cross tolerant with the 25i NBOMe or Moxy is cross tolerant of re-dosing with itself within three days (more likely -as the cross tolerance should have theoretically kicked in Friday) or maybe its cross tolerant 25i to Moxy and not Moxy to 25i?
Further research is needed, anyone please weigh in if you have info.
We do know now that 1g of GHB does NOT get us there (We have learned that with practically every substance we use except alcohol, we need to double the regular dose to get the 'standard' effects regular users get. This sucks because it means our chem costs effectively double and/or our stash-life halves!) *'We' means me, not two users*
Last night we tried, as suggested on Blue Giraffe thread, 2g of GHB with titrated re-doses, we did 'feel' it, as a woozy feeling, we did not get jiggy at all on this dose, so we think that we used too soon after that first dose on Thursday.
We also re-dosed GHB 1g at 45 mins,
and nothing much happened,
then .60g at 40mins further in,
and finally 1g another 30mins in,
thereafter we decided to save what was left of the GHB cos this is just wasting it, to NO EFFECT.
Bear in mind we're also bumping a shitload of good resiny weed, about every ten to twenty minutes, this combo should have knocked out a racehorse, but we're like 'Ok when is this combo of aphrodisacs gonna show us some love?'
We just got moderately (THC) high last night, the rest was wasted.
Maybe we should set the THC bumps aside and space out the using by at least a week, to get our moneys worth out of these chems.
BTW, were not a daily user of drugs, these are all first time chems for us except the 25i & THC, and we have been totally clean until this month since last April when we used JWH, 2CB, LSD, and 25i NBOMe all in minimal (too small for us) doses.
We know this post features a lot of other drugs, but as moxy was used with them, we thought we should share..
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@ OP:
You need to know that moxy and 25i NBOMe have a cross tolerance if one intends on piggyback dosing by using the next day
The effects of cross-tolerance will be minimal to non-existant because 25i is an extremely selective 5-HT2A agonist and Moxy has a rather low affinity for 5-HT2A receptors.
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@ OP:
You need to know that moxy and 25i NBOMe have a cross tolerance if one intends on piggyback dosing by using the next day
The effects of cross-tolerance will be minimal to non-existant because 25i is an extremely selective 5-HT2A agonist and Moxy has a rather low affinity for 5-HT2A receptors.
Yes, that's what we expected, but it was not to be, see the post we have just elaborated on our claim above, maybe there's a clue in that extended post you can help us with, cos all we know is, we wasted some good shit last night trying to get to where we wanted to be :(
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@ OP:
You need to know that moxy and 25i NBOMe have a cross tolerance if one intends on piggyback dosing by using the next day
The effects of cross-tolerance will be minimal to non-existant because 25i is an extremely selective 5-HT2A agonist and Moxy has a rather low affinity for 5-HT2A receptors.
i'll just say what i said earlier, and that was that two .5 mg blotters of 25b-nbome provided a rediculous tolerance, and everytime ive done a phenethylamine then a tryptamine after, its been a waste. (unless of course the phenethylamine was more of a stimulant =P)
when im on nbomes i feel like everything in my brain is wide open.
its not a good feeling lol
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Interested. Thanks for the thread!
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@ Motek +1 karma to you, excellent post and contribution on how to use powdered bulking agents for dosing at the microgram (ug) level accurately, without having to source various liquids, containers, syringes, and a calculator. Just what the doctor ordered!
where's motek's post about this? i just ordered some powder moxy and i'm not sure how i will be taking it. i have a mg scale but 2mg is the rounding error for the scale and i want to try at 2mg dose increments. i was thinking of mixing 10mg measured across my 2 scales with about 10 drops of water so that 1 drop ~ 1mg
how are other people on this board consuming their moxy powder?
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I bought my Moxy from Methqualone and they had their Moxy caps mixed with brewing sugar and then capped. ;)
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I bought my Moxy from Methqualone and they had their Moxy caps mixed with brewing sugar and then capped. ;)
Yeah I know BlueGiraffe mix theirs with L-Arginine, seems to be a fairly common (as useful) practice. Sucks for those of us that buy straight powder though. I have a good scale, but it still has a +/-2~3mg error... which matters with something like Moxy.
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I tried 6 mg of moxy a couple of weeks back, which I understand is quite a low dose.
Anyway, it was my first foray into RCs and was quite strange. I'd describe it like kind of having the 'weirdness/trippyness' of LSD but without any mental effects, improved appreciation of music and a generally kinda fucked up feeling. I didn't really get much euphoria -nothing comparable with MDMA anyways- more just a strange pleasantness (this might improve with a higher dose?). Visually there was some slight depth perception change and a slight movement of a shodowy pattern on the ceiling, but nothing very noticable at this dose.
;D
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I bought my Moxy from Methqualone and they had their Moxy caps mixed with brewing sugar and then capped. ;)
Yeah I know BlueGiraffe mix theirs with L-Arginine, seems to be a fairly common (as useful) practice. Sucks for those of us that buy straight powder though. I have a good scale, but it still has a +/-2~3mg error... which matters with something like Moxy.
I wonder how BlueGiraffe measures his doses? i doubt he has a super expensive and precise scale. maybe he just thoroughly mixes 100mg with some other ingredients and makes his pills that way?
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I bought my Moxy from Methqualone and they had their Moxy caps mixed with brewing sugar and then capped. ;)
Yeah I know BlueGiraffe mix theirs with L-Arginine, seems to be a fairly common (as useful) practice. Sucks for those of us that buy straight powder though. I have a good scale, but it still has a +/-2~3mg error... which matters with something like Moxy.
I wonder how BlueGiraffe measures his doses? i doubt he has a super expensive and precise scale. maybe he just thoroughly mixes 100mg with some other ingredients and makes his pills that way?
What sucks with those capped moxy is that their price is 10-20 times more expensive than the straight powder. Makes you think twice.
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Indeed it does... I think I'll just use my mg scale and aim for around 10 mg, that way if I am off by 2mg my range is only 12mg-8mg. Still enough for a decent experience i think.
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Hi all, just wondering about body weight to dosage ratio. I weigh around 185-190lbs and am planning on taking 10-12mg. My partner for the experience weighs only 115lbs though and is much less experienced with psychedelics. I was thinking of giving her around 9mg. What do people think about that dosage? Or is there more information about dosage by bodyweight?
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Tried 4/5mg of Moxy on the weekend and the comeup was pretty weird.. but when it hit me I'd describe it as enjoyable. A lot of things seem to be happening which would have usually stressed me out but I just sat there laughing at the situation. Felt quiet nice, almost tingly. Very minor visuals, almost unaccountable. A friend also came over out the blue when the high was wearing off and I could hold a conversation easily with them.
One thing I did notice is that for the next couple of days my dreams where very weird.
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Has anyone been smoking Moxy and if so, what's the best way to do it ? I've read that even putting some in a joint would work.
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Has anyone been smoking Moxy and if so, what's the best way to do it ? I've read that even putting some in a joint would work.
I once vaped some from foil. Do it outside because the smell will stay in the air for a long time. It gave me a weird trippy buzz for a few minutes, with lingering after effects for a few hours (so Erowid is correct on this). It was kinda like I imagine coming up on DMT feels like.
Is freebasing necessary with this substance?
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I tried Moxy for the first time yesterday, I did 3mg from BlueGiraffe. Pretty intense! Took about 45 minutes to start showing signs and it got more pronounced at 1 hour mark, tons of energy, body felt light, tactile sensations were enhanced, sex/masturbation is nuts on it, really impressed me on that part! Also music is incredible on the stuff! I felt like the music was vibrating at a physical level through me, very intense! Felt like my senses were amplified and my vision was faster.
Pretty good lil drug I must say!
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just got around to trying some of awakened350's moxy i bought a few months back
first time trying this so i measured 10mg on my .001mg scale and mixed it with 10ml water to control my dosage at 1mg per ml roughly.
0:00 took 4ml to start. bitter with bitter aftertaste but not awful. doesn't really wash away with more water so i ate a candy and that took care of it
0:30 starting to feel something. i don't feel like myself but i don't know what i'm feeling yet. noticing time dilation already
1:00 slightly heavy body load. feeling a bit tired and slow and buzzy all over. slight happy feeling
1:05 redosed another 2mg redose
1:40 feeling more energetic and more happy. kind of feels like i'm drunk. body still tingling and there's a noticeable element of sensualism
1:50 starting to see some open eye visuals. very slight breathing/pulsating of things. peripheral vision is very distracting
2:05 redosed another 2mg
2:30 still feeling good. really weird mix of body load but also energetic
3:00 cev kicking in more noticeably. visuals start as fractals but then join to form solid shapes that form scenes that are very realistic and lifelike.
3:30 just laying around and i feel like my body is not my body. i felt like i'm a house and my brain is walking through my body and opening different rooms. kind of weird. some visuals are a bit overwhelming in that it's an image just zooming in and out of itself. not unpleasant but definitely new
4:30 visuals are mostly gone. still feeling body buzzing and slight tired happy sensation
5:00 had some food and felt some nausea
overall it was an interesting experience. i can definitely see how the characteristics of the drugs changes in the low, medium, and higher doses to go from something very party-friendly to very psychedelic. i'll need to experiment more