Silk Road forums
Discussion => Silk Road discussion => Topic started by: Okamiyasha on January 07, 2013, 12:55 am
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What in the heck is complexed even mean?
Cyclodextrin for Complexing
Cyclodextrin is a ring shaped molecule that is used as a delivery system for other chemicals. Other molecules can fit inside the ring. The ring absorbs chemicals and in the case of 25I-NBOMe, 25C-NBOMe, 25D-NBOMe, and butyr-fentanyl – it prevents the molecule from degrading. Cyclodextrin is completely legal. It is not a research chemical and will continue to be around.
Why do I need it?
Cyclodextrin is extremely useful for increasing the bioavailability of the 25X-NBOMe class of chemicals along with butyr-fentanyl. This includes research chemicals like 25I-NBOMe, 25C-NBOMe, and 25D-NBOMe. Without the help of cyclodextrin, these research chemicals are reported to have trouble making it past harsh conditions inside the body such as stomach acid and polar-nonpolar barriers. Some users say that it that cyclodextrin doesn’t make a big difference, but since it’s so cheap its worth picking up anyways. For butyr-fentantyl, it also serves to increase the weight of inert chemical which reduces its danger.
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In a nut shell cyclodextrin is sugar that is used (in our context) to encapsulate hydrophobic drugs to aid in sublingual administration.
Literally tons of research has been performed on cyclodextrin complexes for the administration of steroids. These are off the top of my head, but studies have shown cyclodextrin to increase sublingual bioavailability of otherwise hydrophobic molecules from 40% to 90% when the substance is held for twenty minutes.
Cyclodextrin will favor EtOH over 25x so you need to dry it or use extra cyclodextrin. It takes two to encapsulate a molecule so using molar mass and the 2:1 ratio it is easy calculate the necessary amount.
*and 25x compounds are destroyed by stomach acid. Don't try eating them.
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I took this substance once, and after the initial come-up I remember nothing at all, but I feel like I remember it all?
It was crazy! :o :o :o :o :o :o :o