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Discussion => Drug safety => Topic started by: paxpax on July 31, 2012, 03:41 pm

Title: MDMA Dosing Guide - Derived from Pihkal
Post by: paxpax on July 31, 2012, 03:41 pm
Hey Everyone,
  I thought I would post a chart for anyone curious on how to properly dose on MDMA. I did not create the chart but it is based on Shuligan Pihkal - 109. The recommendations are sound and seem to produce the best effects with the least amount of hangover. It is worth noting that two doses should be used. An initial does and a booster after 1.5 hours of taking initial dose. It is worth noting the booster is taken 1.5 hours after dose and not 1.5 hours after effects are felt. For the math guys out there dosing is 1.5mg/kg initial and .5mg/kg booster

Dosages by weight, including booster.
Weight lb.  Kg            Initial   Booster    Total Dose
90lb            40.9Kg    61mg    20mg    82mg
100lb    45.5Kg    68mg    23mg    91mg
110lb    50.0Kg    75mg    25mg    100mg
120lb    54.5Kg    82mg    27mg    109mg
130lb    59.1Kg    89mg    30mg    119mg
140lb    63.6Kg    95mg    32mg    127mg
150lb    68.2Kg    102mg    34mg    136mg
160lb    72.7Kg    109mg    36mg    145mg
170lb    77.3Kg    116mg    39mg    155mg
180lb    81.8Kg    123mg    41mg    164mg
190lb    86.4Kg    130mg    43mg    173mg
200lb    90.9Kg    136mg    45mg    181mg
210lb    95.5Kg    143mg    48mg    191mg
220lb    100.0Kg    150mg    50mg    200mg
230lb    104.5Kg    157mg    52mg    209mg
240lb    109.1Kg    164mg    55mg    219mg
250lb    113.6Kg    170mg    57mg    227mg


--EDIT--
Some other points worth mentioning: The table above assumes pure MDMA.  I  think most molly falls into the >75% range here at SR, dose should be adjusted as necessary. For reference most pills contain between 100-150mg MDMA most commonly on the lower end between 100-125mg

Title: Re: MDMA Dosing Guide - Derived from Pihkal
Post by: HOUSE on July 31, 2012, 05:59 pm
So would this apply for a first time (or first few times only)?

Because I cannot imagine myself being able to roll with just taking 100mg (I weigh 51-53kg) at this stage.

Surely like with everything else, there will be increasing tolerance. As the "magic" disappears, the only way to win some of it back is by taking more.

Either this guide is on the low side, or else I'm a pig - because I've taken more than twice the recommended dose, and I've known people to FAR exceed anything on that chart.
Title: Re: MDMA Dosing Guide - Derived from Pihkal
Post by: paxpax on July 31, 2012, 06:29 pm
House:
  Purity and exp certainly play a roll in dosage. If one is at the point of having to take massive doses to achieve a decent roll it is probably time switch out MDMA for another favored psychedelic for some time. IIRC overdose / toxic levels for humans is close to 3 grams (citation needed) so it is possible to take a very large dose without setting a meeting with St Peter, although doses over the levels recommended above have diminishing returns and greatly exasperate side effect symptoms.
  Personally I weigh 200 pds, my preferred dose 160/50, total dose 210mg, about 15% over recommended. I also allow almost 2 months between sessions.
  A simple anaology. View your brain as a sponge soaked in water. A proper squeeze will wring the sponge of a majority of the absorbed water with very little effort. The Sponge will spring back and be none the worse for wear. Sure you could go ape shit on the sponge and get out every last drop, but what would that do to the sponge?

---EDIT---
After reviewing my notes I had to update the chart above. Dosages listed above assume 100% MDMA. Amount of molly consumed should be adjusted for purity. For ex, 75% pure Molly should increase dose by 25%.
Title: Re: MDMA Dosing Guide - Derived from Pihkal
Post by: tomropes on July 31, 2012, 08:53 pm
Do people who suffer from chronic depression have to take more?

For my first mdma experience, I took 100 mg, waited an hour, got no buzz, took another 100 mg and still got zero buzz. The vendor seems to have reputable product according to other patrons.
Title: Re: MDMA Dosing Guide - Derived from Pihkal
Post by: paxpax on July 31, 2012, 09:11 pm
Hi Tom:
  It depends on the depression and more so on any medication you may be taking to combat depression.

First, if you are currently taking an SSRI then you will be unable to have any effect from MDMA and you also risk seratonin syndrome, which is possibly life threatening. It has been postulated that users with a lengthy past history of using an SSRI or MAOI may have their receptors  permanently modified to the point that MDMA will no longer bind. 

If you are currently on anti-depressants you would need to stop medicating. Prozac, by far the most commonly prescribed unfortunately has the longest half life. A min of 30 days would be needed in an otherwise healthy individual,

If you are diagnosed as depressed and not on medication it would depend on how your brain chemistry differs from that of a non depressed individual. To borrow from my sponge analogy earlier: Your sponge may hold less water. But it still holds water so you should have some type of effect.

My guess is either you are currently on anti-depressants, are only recently off of them or had porr quality MDMA.



Title: Re: MDMA Dosing Guide - Derived from Pihkal
Post by: tomropes on July 31, 2012, 09:31 pm
Yes I am on anti-depressants at the moment, I had not suspected they were the reason for lack of a buzz.

I also tried one DEFQON ecstasy pill from schizofreen recently this past weekend and all it did was make me break a sweat so I don't think it was poor quality products from two completely different vendors.

Thanks for your input, you were very helpful.
Title: Re: MDMA Dosing Guide - Derived from Pihkal
Post by: stolea2269 on July 31, 2012, 11:52 pm
Keep in mind that his dosing strategies were for therapeutic work.

I find that recreational use demands a little bit higher dose.

The golden standard of 120mg + 40mg booster seems to be ideal for regular-sized people.