Silk Road forums

Discussion => Drug safety => Topic started by: zipstyle on July 13, 2013, 07:33 pm

Title: Can propranolol (Inderal) help prevent heart attacks or similar?
Post by: zipstyle on July 13, 2013, 07:33 pm
Just got some propranolol to calm the jitters down that I get from time to time on my meds (dextroamphetamine) and was wondering if propranolol could also be used as a reasonable way to prevent adverse side effects from cardiac over-stimulation. I know that it basically slows down the heart rate and lessens the activity of the adrenergic receptors (A2 if I remember correctly?), so could that also mean that it will help in the case of a stimulant overdose?
Title: Re: Can propranolol (Inderal) help prevent heart attacks or similar?
Post by: tree on July 13, 2013, 07:57 pm
I remember reading on erowid that propanolol and derivatives actually increased the risks of cardiac events when mixed with stimulants, especially with ephedrine... I wouldn't use it with amphetamine either, stick to benzos they're also effective and safe when mixed with stimulants.
Title: Re: Can propranolol (Inderal) help prevent heart attacks or similar?
Post by: zipstyle on July 13, 2013, 08:02 pm
I remember reading on erowid that propanolol and derivatives actually increased the risks of cardiac events when mixed with stimulants, especially with ephedrine... I wouldn't use it with amphetamine either, stick to benzos they're also effective and safe when mixed with stimulants.

Hmm, that's interesting. After doing some reading of my own, I found the opposite to be true.
http://www.erowid.org/references/refs_view.php?ID=3610&S=propranolol
Title: Re: Can propranolol (Inderal) help prevent heart attacks or similar?
Post by: tree on July 13, 2013, 08:33 pm
Here's the reference I was talking about : https://www.erowid.org/pharms/betablockers/

I would rather take benzos over propanolol to come down to be on the safe side. Although some sources say that propanolol is recommended in ephedrine overdosage, I don't know if they're valid and it's maybe not true for using ephedrine or amphetamine and propanolol daily. Using it daily to prevent your heart from beating too fast could maybe make things even worse, but dextroamphetamine doesn't really affect the heart that much so what could interact badly with ephedrine and racemic amphetamine could be not as much of a concern for dextroamphetamine.

Maybe good old potassium would be better to avoid cardiac adverse effects, at least it's also not addictive and is healthy :P
Title: Re: Can propranolol (Inderal) help prevent heart attacks or similar?
Post by: zipstyle on July 13, 2013, 09:16 pm
Thanks for expanding on what you said earlier!
Great info :) +1