Silk Road forums

Discussion => Drug safety => Topic started by: ROOR521 on May 22, 2012, 01:28 am

Title: 2cb cross tolerance
Post by: ROOR521 on May 22, 2012, 01:28 am
I am going to a festival this weekend and I was planning to to bring some mushrooms, lsd, mda and more lsd. And consume in this order but I recently purchased some 2cb to try for the first time and was thinking of throwing that in the mix as well or to replace my mushrooms.  Does anybody have any experience with 2cb having a cross tolerance with lsd or mda?
Title: Re: 2cb cross tolerance
Post by: ROOR521 on May 22, 2012, 09:12 pm
Bump for info
Title: Re: 2cb cross tolerance
Post by: sollemnis on May 22, 2012, 09:28 pm
I'm not certain but I think 2c-b binds to a different receptor to LSD... So I wouldn't have thought there's a cross tolerance. Could be wrong... But I remember reading it somewhere on these forums.
Title: Re: 2cb cross tolerance
Post by: sollemnis on May 22, 2012, 09:31 pm
'Unlike most hallucinogens, 2C-B has been shown to be a low efficacy serotonin 5-HT2A receptor partial agonist[8] or even full antagonist' from Wikipedia.
Title: Re: 2cb cross tolerance
Post by: ROOR521 on May 22, 2012, 09:38 pm
Cool thanks for the reply. Guess I'll just give it a try and find out. lol
Title: Re: 2cb cross tolerance
Post by: sollemnis on May 22, 2012, 09:42 pm
Cool thanks for the reply. Guess I'll just give it a try and find out. lol

Someone with a better understanding will probably tell you. I could be completely wrong but I think I read about it on here. Good luck anyway :)
Title: Re: 2cb cross tolerance
Post by: ROOR521 on May 23, 2012, 12:50 am
No worries man. I was planning on finding out for myself anyway but I figured if someone on here says taking the 2cb the day before lsd will greatly diminish the lsd experience then maybe I would reconsider the 2cb for a later time.  Always nice when your problems have to do with how to best consume all the drugs I have. lol
Title: Re: 2cb cross tolerance
Post by: sollemnis on May 23, 2012, 12:55 am
No worries man. I was planning on finding out for myself anyway but I figured if someone on here says taking the 2cb the day before lsd will greatly diminish the lsd experience then maybe I would reconsider the 2cb for a later time.  Always nice when your problems have to do with how to best consume all the drugs I have. lol

Well to point out the obvious, do the acid first. 2c-b is much cheaper... wasting a bit of 2c-b wouldn't be as expensive  ::). Yeah, you're not the only one! I always try  to get the most from my drugs - I pay for them, why not?  :D