Silk Road forums
Discussion => Newbie discussion => Topic started by: incognito22 on February 03, 2013, 11:28 pm
-
Can someone tell me the cross tolerance between Ecstacy, LSD, Shrooms, DMT, and Mescaline
I never knew you couldn't do Shrooms and LSD back to back with diminished tolerance...thank God I thought of this before my shrooms arrive this week.
What about ecstacy, DMT and mescaline? How do all of these 5 drugs interact? Any information you would like to add to the topic of cross-tolerance would be appreciated as I'm going to have Acid, shrooms, molly and DMT all at the same time and wondering how I should take it all. And don't tell me "YOU SHOULD WAIT A MONTH BETWEEN TRIPS BECAUSE IT'S BAD FOR YOUR BRAIN"...I don't want to hear that. I'm just wondering about tolerance of it all. Thanks a lot.
-
lol no one has even viewed this thread? cmon guys.
-
i like mdma and shrroms the best
-
I'm also interested in this topic, hopefully a knowledgeable forum user can enlighten us
-
very interested too
-
I can't speak for the drugs you listed as I've never combined them or heard of someone doing so, but something that might be of interest: I once had one or two of those legal high pills, having nothing "real" to take and passing by a head shop. For a bunch of herbs in a gel cap, it was surprisingly good. Anyway, someone came around with salvia, which I smoked a good bowl of, and the trip was WAY longer. It wasn't super strong but had that distinct distortion of spatial awareness. After a few minutes when everyone else had pretty much returned to baseline, I was still rocking side to side and mumbling. I have no idea what the herbal mix was, but it obviously prolonged (but not amplified) the effect of sally... odd.
MDMA obviously interacts with serotonin and that whole hormonal system in a big way, but I think acid does too, to some extent. That might mean the receptors being over-stimulated, but I don't know enough about neurochemistry to say if that would affect tolerance...
-
cleartext link AND a pdf - hxxp://www.maps.org/research/cluster/psilo-lsd/cns-neuroscience+therapeutics_2008-passie.pdf
viewer - http://view.samurajdata.se/
There is partial cross-tolerance (depending on whether LSD is given first or second) among LSD, mescaline, and psilocybin [168–170]. The most complete cross- tolerance is to mescaline in LSD-tolerant subjects. One study suggested that one-way cross-tolerance from LSD to DMT does not occur [171]. Studies with delta-9- tetrahydrocannabiol (THC) in subjects tolerant to LSD did not demonstrate a cross-tolerance between these drugs [172,173]. There is no cross-tolerance between LSD and amphetamine [169]. See Wyatt et al. [174] and Hintzen [50] for a complete review of tolerance and cross-tolerance studies with LSD.
The Hintzen/Passie book referenced in that quote (50) can be found online, "The Pharmacology of LSD: A Critical Review."
You want page 81, or search within for "Tolerance and cross-tolerance" and/or "table 2.13".
hope that helps
Iris