Silk Road forums

Discussion => Newbie discussion => Topic started by: flettino on February 22, 2013, 12:02 am

Title: Websites for drug production?
Post by: flettino on February 22, 2013, 12:02 am
I'd really like to start making drugs, like MDA and stuff like that.

Is there a TOR website which has discussions about drug production ? even non tor websites, i can't find them anywhere.

Thanks, F.
Title: Re: Websites for drug production?
Post by: flettino on February 22, 2013, 12:33 am
Bump
Title: Re: Websites for drug production?
Post by: jdtram27 on February 22, 2013, 12:46 am
So, there are plenty of places you can find synthesis's. The real problem is getting reagents. Sure you may find some precursors but you will be damn hard pressed to have everything you need. MDA and the like are much more difficult to synthesize than the nasty meth you see getting cooked inside of walmart on the news.

Its pretty clear that you dont possess the general or organic chemistry knowledge to even know what to search for to find the synthesis you are after. Plus, the synthesis that is actually available to you will most likely not be spelled out in some paper on say.. rhodium or the hive or sciencemadness. You have to know what kind of reaction you need to perform etc and then look those up individually. There is also a huge problem that 99.9% of people do not even realize exists.. Paper chemistry is really easy.. Once you get into the lab and start putting dollar signs on everything and start realizing that many reactions are difficult to get to go to more than a 50% or so yield. The financial loss is compounded by the fact that you now have to SEPARATE your products from any side reaction products, as well as any unreacted starting materials.. Which only means more solvents, etc.. Which all gets difficult to remove without a rotovap etc..

 Chemistry is a rather difficult to subject to master, and without a university education(and chemical connects), one will most likely find failure in their path, hopefully not one that ends with an explosion in your face.
Title: Re: Websites for drug production?
Post by: jdtram27 on February 22, 2013, 12:49 am
Check out Shulgins Pihkal & Tihkal, Festers lsd synthesis


BTW, Can you get me some lithium aluminum hydride? Been trying to get some forever.. Use it every day but its strictly controlled
Title: Re: Websites for drug production?
Post by: cabfare on February 22, 2013, 01:11 am
pihkal has recipes for  MDA MDMA  mescaline, 2C-B and many many other compounds
tihkal  has many tryptamine recipes    such as psilocybin and dmt, 5-meo-dmt  etc

firstly your need to study organic chemistry   this may take 2+ years for you
second  before you even think about the precursors   you must consider that most of these recipes involve using glove boxes, fume hoods, bunsen burners. don't be suprised if equipment all together equipment cost money in the thousands



so.. if you think your intelligent enough to learn organic chemistry, have money to invest, and can obtain precursors (some available on SR)     then  thats were you start.

tbh the most marketable drugs are ones that are easy to make though   i.e. meth, heroin, marijuana, cocaine.       
Title: Re: Websites for drug production?
Post by: jdtram27 on February 22, 2013, 01:24 am
list of organic reactions to paper study

Sn1 & Sn2 neucleophilic substitution, - pay attention to inversion of the stereocenter
E1 & E2 reactions
Functional groups including -Aldehydes, Carboxylic acids, Amines, Amides, Ethers, alcohols,
aromatic compounds and reactivity at the alpha position
Oxidation and reduction reactions
Reductive aminations
Oxidative cleavages etc
Jones Oxidation, Swern Oxidation, hypochlorite, manganese, etc.. many many oxidations that can be used
Reductions with Lithal, NaBH4, DibalH, NaCNBH4 Etc.. There are a lot of reduction techniques
Grignard reagents

Ill try to give some extra stuff to read up on as i remember more..

I can use
Oxalyl Chloride
NaBH4
NaCNBH4
Borane THF mix
THF
Ether
PyBOP
BOP
dimethylamine
Diethylamine
methylamine
triethylamine
DCM

Title: Re: Websites for drug production?
Post by: cabfare on February 22, 2013, 01:32 am
list of organic reactions to paper study

Sn1 & Sn2 neucleophilic substitution, - pay attention to inversion of the stereocenter
E1 & E2 reactions
Functional groups including -Aldehydes, Carboxylic acids, Amines, Amides, Ethers, alcohols,
aromatic compounds and reactivity at the alpha position
Oxidation and reduction reactions
Reductive aminations
Oxidative cleavages etc
Jones Oxidation, Swern Oxidation, hypochlorite, manganese, etc.. many many oxidations that can be used
Reductions with Lithal, NaBH4, DibalH, NaCNBH4 Etc.. There are a lot of reduction techniques
Grignard reagents

Ill try to give some extra stuff to read up on as i remember more..

I can use
Oxalyl Chloride
NaBH4
NaCNBH4
Borane THF mix
THF
Ether
PyBOP
BOP
dimethylamine
Diethylamine
methylamine
triethylamine
DCM

cool :) this will be good for when i have my comp with me but not my books
i'm still just dipping my toes into the ocean known as chemistry    so i'm familiar with about  half of what you just posted
Title: Re: Websites for drug production?
Post by: jdtram27 on February 22, 2013, 01:56 am
Functional group transformations.
Enols & Enolates
Aldol reaction
PyBOP and BOP as amide condensing reagents
Add To functional groups : Nitrile, Nitro, Diazo, Acid Chloride, Acid Anhydride, Ketone, Double & Triple bonds



If you want to be a boss and make anything....Organometallic reactions like:
Stille
Suzuki
Heck
Shongashira

shits tight..

AFter you have all this down, then get yourself into the lab and learn how to actually make these chemicals do what they are fucking supposed to LMAO!

Then, after you have all that down.. Get yourself a solid connect for lab supplies (this is actually really fucking hard to find).. And PM me up when it happens so i can get some of them tasty reagents!

Sorry to thread jack, i need 50 and i figured i would use this as my own personal list of shit. IF anyone would like to add any organic shit i missed feel free to do it.
Title: Re: Websites for drug production?
Post by: jdtram27 on February 22, 2013, 02:01 am
add halides to the list of functional groups.

I could sure use some

Ergotamine
Ergonovine
Nitroethane
Piperonal
Piperic Acid
Any MNO4 salt
Mercury or its salts
LAB GRADE acetone
Mg turnings


A cheap Rotovap
Title: Re: Websites for drug production?
Post by: FieryDahlia on February 22, 2013, 06:46 am
I'm sure everyone's thought like this, then they get overwhelmed with the information and risk and give up. The people out there who do make this stuff are incredible.
Title: Re: Websites for drug production?
Post by: Cotchept on February 22, 2013, 06:52 am
erowid?
Title: Re: Websites for drug production?
Post by: jdtram27 on February 22, 2013, 01:24 pm
Lab techniques to learn.

Distillation (regular, dry, steam, vacuum, fractional, vac/frac, etc)
Acid base extraction
reflux
etc..
Title: Re: Websites for drug production?
Post by: blojan on February 22, 2013, 02:11 pm
I always wonder what the yield is of the illicit chemists. Since purification of the product is usually the most difficult, I would think they have some perfect technique with extremely high yields so they only have to wash and dry.
Title: Re: Websites for drug production?
Post by: onetwothree on February 22, 2013, 02:43 pm
I don't know exactly what you're trying to make, but if it's meth, they seem to use advanced techniques for highest purity in a weekly documentary called "Breaking Bad".
Title: Re: Websites for drug production?
Post by: modziw on February 22, 2013, 03:57 pm
Holy crap this thread gave me a headache!

modzi
Title: Re: Websites for drug production?
Post by: cabfare on February 23, 2013, 04:28 am
erowid?
\


erowid have tihkal and pihkal  but other than that i don't know of any complex syntheses
more things like extractions, growing tips, fairly simple preparations of substances  etc
maybe i haven't been looking at the right drugs though?
Title: Re: Websites for drug production?
Post by: triggerJay90 on February 23, 2013, 04:30 am
Cant help ya there mate :(
Title: Re: Websites for drug production?
Post by: cabfare on February 23, 2013, 05:19 am
found interesting article on  purification of street dope on erowid
basically  A/B extraction  but good read imo
http://www.erowid.org/chemicals/heroin/heroin_info5.shtm


anyone have links for process of making ketamine,  diazepam, methadone,  dextroamphetamine/levoamphetamine ( think product makes mixed of both isomers. but not positive)

Title: Re: Websites for drug production?
Post by: fullofspice on February 23, 2013, 06:07 am
Everything and more:

http://www.erowid.org/archive/rhodium/chemistry/index.html