Silk Road forums
Market => Product offers => Topic started by: National Direct on March 04, 2013, 07:40 pm
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Hey guys! As we at National Direct are working well so far planning our logistics for future sale of affordable Armofinil/Modafinil, we are at the stage where we need some information from the community as a whole, and for my future potential customers. I get a lot of messages asking when I will have Modafinil in stock. I also get an equal amount of messages asking when we will have Armodafinil in stock.
Now, if you don't know the difference between the two, Armodafinil (Nuvigil), is an isolated stereoisomer of Modafinil, which is thought to produce all the desired effects Modafinil. The other stereoisomers (accounting for half of the weight of racemic modafinil), are thought to be unnecessary to produce the effects desired from users of this drug, and the removal of these mostly inactive stereo-isomers have been reported to potentially reduce adverse side effects, since they are inactive, their removal would, in theory make a cleaner drug.
(Note: Pharmaceutical companies very often use the technique of isolating stereoisomers and enantiomers to improve profit on patent-expired products, by effectively obtaining a patent for the isolated parts and agressively marketing it as far more effective than the patent-expired whole chemical. An examples of this is citalopram's (Celexa) re-introduction as escitalopram (Lexapro, Cipralex), where the (S)-stereoisomer is isolated, as this enantiomer is what produces the desired SSRI effects. The recommended dosages are exactly half of what it was for the parent compound (citalopram is commonly prescribed at 20-40mgs, and escitalopram at 10-20mg)
*In the past many substances isolated the levo and dextro isomers of a substance because of reasons beyond removing inactive parts. Products such as dextr-amphetamine produce very different effects from levo-amphetamine, where levo-amphetamine produces more physical stimulation via primarily norepinephrine reuptake, as opposed to d-amph, which has a much higher affinity to dopamine transporters, which produces more of a mental stimulation and euphoria at higher doses. Dextromethorphan (DXM, a common OTC cough suppresant/dissociative at high doses) on the other hand is an SRI and NMDA receptor antagonist, whereas levomethorphan produces much different effects, acting as an opioid analgesic.
Modafinil is not two different drugs with different mechanism of action like those described above; and is more like citalopram, where one enantiomer is pharmacologically active. This is where Nuvigil comes in as armodafinil, the active part of modafnil, with exaggerated claims are made to make it seem far superior than modafinil, when in reality the effects are almost identical for most users, although pharmacokenetically, it's been suggested that the inactive side can affect how the active part is absorbed and metabolised in some individuals.
You can expect the dose you need with modafinil to be halved when taking armodafinil, and vice versa.
Now, armodafinil has a stigma with educated people because it is known to have a higher pricetag due to re-branding as an attempt to restart the product life cycle. I will be selling armodafinil at affordable rates, and 150mg of armodafinil will cost you less than 300mg of modafinil when you buy from me. I personally don't notice a difference in the two and feel that 150mg of armodafinil is equivalent to 250mg modafinil in my experience.
I would appreciate any experiences you have on both products, as it will help me to better stock products that people want. Does modafinil seem to work better for you? Worse? The same? (assuming the dose is double that of your armodafinil experience).
I personally take armodafinil (225mg as 1.5 150mg pills) when available as it is cheaper to achieve the effects I want than modafinil. In my mind I think that if people knew more about the differences between the compounds, many modafinil users would try armodafinil and find that the effects are the same, making armodafinil cheaper. Since this is not the case I want to know if there is a reason I should stock modafinil, as I would prefer selling armodafinil only to give my customers the best bang for their bitcoin.
I appreciate all the feedback I get!
The expected date of availability of armodafinil and possibly modafinil is early- to mid-April.
Thanks for your time!
N. Direct
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So far we got 2 votes (100%) preference for modafinil. I'm curious what the reasoning to this preference is if the price of the dosage requiring similar effects is the same or cheaper.