Silk Road forums

Discussion => Drug safety => Topic started by: mugiwara930 on May 09, 2013, 01:10 pm

Title: Parachuting heroin?
Post by: mugiwara930 on May 09, 2013, 01:10 pm
Anyone ever try this?
Title: Re: Parachuting heroin?
Post by: shimbabwe on May 09, 2013, 01:11 pm
waste of dope
Title: Re: Parachuting heroin?
Post by: londonpride2 on May 09, 2013, 01:36 pm
Oral use of heroin is less common than other methods of administration, mainly because there is little to no "rush", and the effects are less potent.[68] Heroin is entirely converted to morphine by means of first-pass metabolism, resulting in deacetylation when ingested. Heroin's oral bioavailability is both dose-dependent (as is morphine's) and significantly higher than oral use of morphine itself, reaching up to 64.2% for high doses and 45.6% for low doses; opiate-naive users showed far less absorption of the drug at low doses, having bioavailabilities of only up to 22.9%. The maximum plasma concentration of morphine following oral administration of heroin was around twice as much as that of oral morphine.[69]
Title: Re: Parachuting heroin?
Post by: I_have_questions on May 09, 2013, 03:14 pm
Some twat probably has, yea. It's a complete waste though, oral BA for H is ~35%. Snorting yields a higher BA.