Silk Road forums

Discussion => Drug safety => Topic started by: PoisonedDestiny on March 15, 2012, 08:07 am

Title: Ketamine and Opiate Tolerance/Withdrawal
Post by: PoisonedDestiny on March 15, 2012, 08:07 am
i've read alot of intriguing reports about MXE and ketamine affecting opiate tolerance.  i suppose the NMDA action has something to do with it, possibly by propagating endogenous opioid receptors in the user? 
i've also heard it can help kill physical addiction to opiates.  i've read different things, but some suggest very low doses (10 to 15 mg) a couple times a day after complete termination of opiate use will prevent withdrawal.  and instead of delaying it (like opiate replacements) it literally overwrites it. 
anyone had experience using it for either purpose? 

*destiny*
Title: Re: Ketamine and Opiate Tolerance/Withdrawal
Post by: mju7 on March 15, 2012, 08:34 am
Ketamine is the best drug for opiate withdrawal. Just go cold turkey on whatever opiate and take small doses of Ketamine to counteract the withdrawal. Continue for about a week and then quit the Ketamine and your cured.
Title: Re: Ketamine and Opiate Tolerance/Withdrawal
Post by: tordemon on March 16, 2012, 12:26 am
IIRC ketamine is converted in your stomach into a more opiate-like version, and so oral administration is very effective for withdrawal treatment. I think it's called like norketamine or something like that. That might only be DXM, though...
Title: Re: Ketamine and Opiate Tolerance/Withdrawal
Post by: PoisonedDestiny on March 16, 2012, 06:00 am
thanks everyone.  oral route does seem like best for this use.  i understand it increases duration which seems as though it would enhance the opiate withdrawal suppression.

i wonder why this isn't medically accepted?  seems far more painless then using replacement or maintenance therapy
i remember being put under for a tooth extraction.  they used fentanyl and a benzo (along with N2O and propolene) to put me under.  then i got two shots of K when i started to wake up twice during. 
when i finally came to i was in a K hole and still exploding with fentanyl euphoria.  hehe it was amazing.

*destiny*
Title: Re: Ketamine and Opiate Tolerance/Withdrawal
Post by: mju7 on March 16, 2012, 04:48 pm
DO NOT TAKE KETAMINE ORALLY!

It metabolises into norketamine which is highly alkaline. This will cause intense pain in your stomach for days, you will be lucky if you can walk with such pain. It is better to just insuffulate and re-dose as required.
Title: Re: Ketamine and Opiate Tolerance/Withdrawal
Post by: PoisonedDestiny on March 22, 2012, 05:34 am
DO NOT TAKE KETAMINE ORALLY!

It metabolises into norketamine which is highly alkaline. This will cause intense pain in your stomach for days, you will be lucky if you can walk with such pain. It is better to just insuffulate and re-dose as required.

oh wow, wasn't aware of that.  a friend of mine once crushed half a vial orally, but i didn't see him for a few days after.  he must have been in owie land. 
sublingually is ok right?  like placing a drop under the tongue and holding?  i ask because my partner wants to try k for the first time and she doesn't sniff anything.

*destiny*
Title: Re: Ketamine and Opiate Tolerance/Withdrawal
Post by: rise_against on March 22, 2012, 05:58 am
i blend mine into my morning smoothie.
Title: Re: Ketamine and Opiate Tolerance/Withdrawal
Post by: mju7 on March 22, 2012, 10:03 am
DO NOT TAKE KETAMINE ORALLY!

It metabolises into norketamine which is highly alkaline. This will cause intense pain in your stomach for days, you will be lucky if you can walk with such pain. It is better to just insuffulate and re-dose as required.

oh wow, wasn't aware of that.  a friend of mine once crushed half a vial orally, but i didn't see him for a few days after.  he must have been in owie land. 
sublingually is ok right?  like placing a drop under the tongue and holding?  i ask because my partner wants to try k for the first time and she doesn't sniff anything.

*destiny*
I have no idea if it even works sublingually. I would avoid it though. Go insuffulated or IM/IV only, if your girl has a problem with that then Ketamine is not for her.

Does anyone know if this works as well with MXE ?
Probably not because MXE is very shit. Tiletamine could work, but I think it will not be as good as Ketamine.